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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRIT1
All Species:
27.27
Human Site:
S391
Identified Species:
66.67
UniProt:
O00522
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00522
NP_004903.2
736
84348
S391
I
T
D
Q
Q
G
R
S
P
L
N
I
C
E
E
Chimpanzee
Pan troglodytes
XP_001165880
736
84342
S391
I
T
D
Q
Q
G
R
S
P
L
N
I
C
E
E
Rhesus Macaque
Macaca mulatta
XP_001101416
736
84321
S391
I
T
D
Q
Q
G
R
S
P
L
N
I
C
E
E
Dog
Lupus familis
XP_539416
736
84378
S391
I
T
D
Q
Q
G
R
S
P
L
N
I
C
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6S5J6
736
83963
S391
I
T
D
Q
Q
G
R
S
P
L
N
V
C
E
E
Rat
Rattus norvegicus
NP_001102088
736
83987
S391
I
T
D
Q
Q
G
R
S
P
L
N
V
C
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521606
418
46918
K118
F
I
V
P
S
V
V
K
D
N
T
K
Y
A
Y
Chicken
Gallus gallus
NP_001026144
737
84255
S392
I
T
D
Q
Q
G
R
S
P
L
N
V
C
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665643
659
75764
H354
Y
R
S
V
E
L
K
H
G
N
N
T
T
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797833
532
60450
G232
P
Q
L
Q
L
P
R
G
G
L
Q
I
F
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.3
98.9
N.A.
94.5
95.2
N.A.
51.2
91.5
N.A.
66.8
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
99.8
99.3
99.7
N.A.
96.4
96.7
N.A.
54
95.7
N.A.
77.1
N.A.
N.A.
N.A.
N.A.
46.4
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
93.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% C
% Asp:
0
0
70
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
70
70
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
70
0
10
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
70
10
0
0
0
0
0
0
0
0
0
50
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% K
% Leu:
0
0
10
0
10
10
0
0
0
80
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
80
0
0
0
0
% N
% Pro:
10
0
0
10
0
10
0
0
70
0
0
0
0
0
0
% P
% Gln:
0
10
0
80
70
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
0
10
0
0
0
0
80
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
0
70
0
0
0
0
0
0
0
0
10
10
10
0
0
% T
% Val:
0
0
10
10
0
10
10
0
0
0
0
30
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _